Mercury and selenium distribution in human kidney cortex.
Identifieur interne : 000612 ( Main/Exploration ); précédent : 000611; suivant : 000613Mercury and selenium distribution in human kidney cortex.
Auteurs : L. Björkman [Suède] ; B. Palm ; M. Nylander ; M. NordbergSource :
- Biological trace element research [ 0163-4984 ] ; 1994.
Descripteurs français
- KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Animaux (MeSH), Chromatographie sur gel (MeSH), Cortex rénal (métabolisme), Exposition professionnelle (MeSH), Femelle (MeSH), Fractions subcellulaires (métabolisme), Humains (MeSH), Liaison aux protéines (MeSH), Mercure (métabolisme), Mâle (MeSH), Odontologie (MeSH), Spectrophotométrie atomique (MeSH), Suidae (MeSH), Sujet âgé (MeSH), Sélénium (métabolisme).
- MESH :
English descriptors
- KwdEn :
- Adolescent (MeSH), Adult (MeSH), Aged (MeSH), Animals (MeSH), Chromatography, Gel (MeSH), Dentistry (MeSH), Female (MeSH), Humans (MeSH), Kidney Cortex (metabolism), Male (MeSH), Mercury (metabolism), Middle Aged (MeSH), Occupational Exposure (MeSH), Protein Binding (MeSH), Selenium (metabolism), Spectrophotometry, Atomic (MeSH), Subcellular Fractions (metabolism), Swine (MeSH).
- MESH :
- chemical , metabolism : Mercury, Selenium.
- metabolism : Kidney Cortex, Subcellular Fractions.
- Adolescent, Adult, Aged, Animals, Chromatography, Gel, Dentistry, Female, Humans, Male, Middle Aged, Occupational Exposure, Protein Binding, Spectrophotometry, Atomic, Swine.
Abstract
Concentration of mercury and selenium were analyzed in tissue fractions of human kidney cortex samples from seven autopsy cases. Total mercury content ranged between 0.3-9.0 nmol Hg/g wet wt. Between 27-61% of the total mercury was found in the 105,000g supernatant of the tissue homogenate from six cases. In kidney cortex from the seventh case, a decreased dentist with the highest concentration of mercury, only 3% of the total mercury was found in the 105,000g supernatant and about 88% in a SDS-insoluble fraction. In this fraction the molar ratio between mercury and selenium was close to 1:1. This study supports results from previous animal studies and indicates that mercury in human kidney cortex could be deposited in forms with different solubility. It could be of importance to speciate different forms of mercury in tissues according to solubility and association to selenium when interpretations of mercury concentrations are made.
DOI: 10.1007/BF02950798
PubMed: 7517163
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Nylander</name></author><author><name sortKey="Nordberg, M" sort="Nordberg, M" uniqKey="Nordberg M" first="M" last="Nordberg">M. Nordberg</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1994">1994</date><idno type="RBID">pubmed:7517163</idno><idno type="pmid">7517163</idno><idno type="doi">10.1007/BF02950798</idno><idno type="wicri:Area/Main/Corpus">000612</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000612</idno><idno type="wicri:Area/Main/Curation">000612</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000612</idno><idno type="wicri:Area/Main/Exploration">000612</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Mercury and selenium distribution in human kidney cortex.</title><author><name sortKey="Bjorkman, L" sort="Bjorkman, L" uniqKey="Bjorkman L" first="L" last="Björkman">L. Björkman</name><affiliation wicri:level="3"><nlm:affiliation>Department of Environmental Hygiene, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Environmental Hygiene, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Palm, B" sort="Palm, B" uniqKey="Palm B" first="B" last="Palm">B. Palm</name></author><author><name sortKey="Nylander, M" sort="Nylander, M" uniqKey="Nylander M" first="M" last="Nylander">M. Nylander</name></author><author><name sortKey="Nordberg, M" sort="Nordberg, M" uniqKey="Nordberg M" first="M" last="Nordberg">M. Nordberg</name></author></analytic><series><title level="j">Biological trace element research</title><idno type="ISSN">0163-4984</idno><imprint><date when="1994" type="published">1994</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Adult (MeSH)</term><term>Aged (MeSH)</term><term>Animals (MeSH)</term><term>Chromatography, Gel (MeSH)</term><term>Dentistry (MeSH)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Kidney Cortex (metabolism)</term><term>Male (MeSH)</term><term>Mercury (metabolism)</term><term>Middle Aged (MeSH)</term><term>Occupational Exposure (MeSH)</term><term>Protein Binding (MeSH)</term><term>Selenium (metabolism)</term><term>Spectrophotometry, Atomic (MeSH)</term><term>Subcellular Fractions (metabolism)</term><term>Swine (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Animaux (MeSH)</term><term>Chromatographie sur gel (MeSH)</term><term>Cortex rénal (métabolisme)</term><term>Exposition professionnelle (MeSH)</term><term>Femelle (MeSH)</term><term>Fractions subcellulaires (métabolisme)</term><term>Humains (MeSH)</term><term>Liaison aux protéines (MeSH)</term><term>Mercure (métabolisme)</term><term>Mâle (MeSH)</term><term>Odontologie (MeSH)</term><term>Spectrophotométrie atomique (MeSH)</term><term>Suidae (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Sélénium (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Mercury</term><term>Selenium</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Kidney Cortex</term><term>Subcellular Fractions</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cortex rénal</term><term>Fractions subcellulaires</term><term>Mercure</term><term>Sélénium</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Animals</term><term>Chromatography, Gel</term><term>Dentistry</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Occupational Exposure</term><term>Protein Binding</term><term>Spectrophotometry, Atomic</term><term>Swine</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Chromatographie sur gel</term><term>Exposition professionnelle</term><term>Femelle</term><term>Humains</term><term>Liaison aux protéines</term><term>Mâle</term><term>Odontologie</term><term>Spectrophotométrie atomique</term><term>Suidae</term><term>Sujet âgé</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Concentration of mercury and selenium were analyzed in tissue fractions of human kidney cortex samples from seven autopsy cases. Total mercury content ranged between 0.3-9.0 nmol Hg/g wet wt. Between 27-61% of the total mercury was found in the 105,000g supernatant of the tissue homogenate from six cases. In kidney cortex from the seventh case, a decreased dentist with the highest concentration of mercury, only 3% of the total mercury was found in the 105,000g supernatant and about 88% in a SDS-insoluble fraction. In this fraction the molar ratio between mercury and selenium was close to 1:1. This study supports results from previous animal studies and indicates that mercury in human kidney cortex could be deposited in forms with different solubility. It could be of importance to speciate different forms of mercury in tissues according to solubility and association to selenium when interpretations of mercury concentrations are made.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">7517163</PMID><DateCompleted><Year>1994</Year><Month>08</Month><Day>02</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>04</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0163-4984</ISSN><JournalIssue CitedMedium="Print"><Volume>40</Volume><Issue>3</Issue><PubDate><Year>1994</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Biological trace element research</Title><ISOAbbreviation>Biol Trace Elem Res</ISOAbbreviation></Journal><ArticleTitle>Mercury and selenium distribution in human kidney cortex.</ArticleTitle><Pagination><MedlinePgn>255-65</MedlinePgn></Pagination><Abstract><AbstractText>Concentration of mercury and selenium were analyzed in tissue fractions of human kidney cortex samples from seven autopsy cases. Total mercury content ranged between 0.3-9.0 nmol Hg/g wet wt. Between 27-61% of the total mercury was found in the 105,000g supernatant of the tissue homogenate from six cases. In kidney cortex from the seventh case, a decreased dentist with the highest concentration of mercury, only 3% of the total mercury was found in the 105,000g supernatant and about 88% in a SDS-insoluble fraction. In this fraction the molar ratio between mercury and selenium was close to 1:1. This study supports results from previous animal studies and indicates that mercury in human kidney cortex could be deposited in forms with different solubility. It could be of importance to speciate different forms of mercury in tissues according to solubility and association to selenium when interpretations of mercury concentrations are made.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Björkman</LastName><ForeName>L</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Environmental Hygiene, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Palm</LastName><ForeName>B</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Nylander</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Nordberg</LastName><ForeName>M</ForeName><Initials>M</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Biol Trace Elem Res</MedlineTA><NlmUniqueID>7911509</NlmUniqueID><ISSNLinking>0163-4984</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>FXS1BY2PGL</RegistryNumber><NameOfSubstance UI="D008628">Mercury</NameOfSubstance></Chemical><Chemical><RegistryNumber>H6241UJ22B</RegistryNumber><NameOfSubstance UI="D012643">Selenium</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002850" 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Nordberg</name><name sortKey="Nylander, M" sort="Nylander, M" uniqKey="Nylander M" first="M" last="Nylander">M. Nylander</name><name sortKey="Palm, B" sort="Palm, B" uniqKey="Palm B" first="B" last="Palm">B. Palm</name></noCountry><country name="Suède"><region name="Svealand"><name sortKey="Bjorkman, L" sort="Bjorkman, L" uniqKey="Bjorkman L" first="L" last="Björkman">L. Björkman</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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